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Table 2 Patient demographic and clinical characteristics

From: Analysis of inappropriate prophylactic use of proton pump inhibitors during the perioperative period: an observational study

Variable

Appropriate (n = 341)

Inappropriate (n = 131)

P

Age (years)

  

0.614

 ≤ 65

258 (75.7)

102 (77.9)

 

  > 65

83 (24.3)

29 (22.1)

 

Gender

  

0.014

 Male

248 (72.7)

80 (61.1)

 

 Female

93 (27.3)

51 (38.9)

 

Medical insurance

  

0.570

 Yes

281 (82.4)

105 (80.2)

 

 No

60 (17.6)

26 (19.8)

 

Intraoperative blood loss (mL)

  

0.002

  < 1500

312 (91.5)

130 (99.2)

 

 ≥ 1500

29 (8.5)

1 (0.8)

 

Grade of surgery

  

0.304

 1–2

18 (5.3)

4 (3.1)

 

 3–4

323 (94.7)

127 (96.9)

 

Concomitant medications

 Antithrombotics

163 (47.8)

26 (19.8)

 < 0.001

 NSAIDs

65 (19.1)

29 (22.1)

0.454

Systemic corticosteroids

  

0.012

 Low dose

200 (58.7)

83 (63.4)

 

 High dose

121 (35.5)

32 (24.4)

 

PPIs-related information

 Dosage form

  

 < 0.001

  Injectable

326 (95.6)

44 (33.6)

 

  Oral

15 (4.4)

87 (66.4)

 

 Time of medical orders

  

 < 0.001

  Workday

341 (100)

115 (87.8)

 

  Weekend

0 (0.0)

16 (12.2)

 

 Types of medical orders

  

 < 0.001

  Standing

316 (92.7)

59 (45.0)

 

  Statim

24 (7.0)

24 (18.3)

 

  Discharge

1 (0.3)

48 (36.6)

 

 Professional titles of doctors

  

 < 0.001

  Junior

24 (7.0)

34 (26.0)

 

  Middle

157 (46.0)

48 (36.6)

 

  Senior

160 (46.9)

49 (37.4)

 

 Number of drugs

  

 < 0.001

  ≤ 10

85 (24.9)

76 (58.0)

 

  11–20

178 (52.2)

46 (35.1)

 

   > 20

78 (22.9)

9 (6.9)

 

 Length of postoperative hospital stay (days)

  

 < 0.001

  ≤ 7

89 (26.1)

93 (71.0)

 

  8–15

156 (45.7)

29 (22.1)

 

   > 15

96 (28.2)

9 (6.9)

 
  1. NSAIDs Nonsteroidal anti-inflammatory drugs