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Table 3 Multiple logistic regression analysis of factors associated with the inappropriate prophylactic use of PPIs during the perioperative period

From: Analysis of inappropriate prophylactic use of proton pump inhibitors during the perioperative period: an observational study

Variable

Assignment

Adjusted OR (95% CI)

P

Gender

Male = 0, female = 1

1.256 (0.649–2.430)

0.499

Age

 ≤ 65 = 0, > 65 = 1

1.098 (0.498–2.420)

0.817

Intraoperative blood loss

 < 1500 = 0, ≥ 1500 = 1

0.242 (0.027, 2.128)

0.201

Antithrombotics

No = 0, yes = 1

0.313 (0.136–0.721)

0.006

Systemic corticosteroids

No = 0

  

Low dose = 1

1.253 (0.366–4.295)

0.720

High dose = 2

1.049 (0.278–3.961)

0.944

Dosage form

Injectable = 0, oral = 1

18.301 (7.497–44.671)

 < 0.001

Time of medical orders

Workday = 0, weekend = 1

 

0.998

Types of medical orders

Standing = 0

  
 

Statim = 1

1.867 (0.780–4.470)

0.161

discharge = 2

11.739 (1.289–106.886)

0.029

Professional titles of doctors

Senior = 0

  

Middle = 1

1.477 (0.725–3.008)

0.283

Junior = 2

9.167 (3.459–24.299)

 < 0.001

Number of drugs

 ≤ 10 = 0

  

11–20 = 1

0.605 (0.299–1.224)

0.162

 > 20 = 2

0.818 (0.220–3.043)

0.764

Length of postoperative hospital stay

 ≤ 7 = 0

  

8–15 = 1

0.515 (0.252–1.056)

0.070

 > 15 = 2

0.262 (0.072–0.951)

0.042